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What does Prednisone treat?

Prednisone (Prednisone Intensol, Rayos) is a glucocorticoid hormonal drug with antiallergic and anti-inflammatory actions.


Indications for the use of Prednisone:

  • Rheumatoid diseases and collagenoses (scleroderma, rheumatoid arthritis, dermatomyositis, and systemic lupus erythematosus).
  • Allergic diseases (including reactions to food and medicines).
  • Diseases of the skin (psoriasis, atopic dermatitis, diffuse neurodermatitis, and eczema).
  • Diseases of the hematopoietic and lymphatic systems (agranulocytosis, leukemia, thrombocytopenic purpura, lymphogranulomatosis).
  • Infectious diseases.
  • Inflammatory diseases.


Application rules

  • With acute symptoms of the disease, Prednisone(Prednisone Intensol, Rayos) is prescribed orally in tablets (0,02-0,08 g per day, divided into 3-4 doses), then the dose of the drug is reduced to 0,005-0,01 g per day.
  • Higher doses of Prednisone taken orally: single dose - 0.015 g; daily dose - 0.1 g.
  • Duration of treatment with Prednisone is determined by the course of the disease and the effectiveness of the treatment.
  • During the treatment, a diet rich in proteins and salts is prescribed.
  • Just as in the treatment of infectious diseases by Cortisone, treatment with Prednisone requires the simultaneous use of antibiotics and other chemotherapeutic agents.


Adverse reactions of Prednisone 

The tendency to water and sodium retention in the body, the development of edema, negative nitrogen balance, hyperglycemia and glycosuria, increased blood pressure, increased fatigue, general muscle weakness, nervous excitement, insomnia, psychoses, convulsions (often occur in children) due to the development of hypoglycemia, hirsutism, amenorrhea, premature birth, and osteoporosis.

To prevent these undesirable reactions during treatment, it is necessary to limit the intake of salt during the treatment with Prednisone and increase the intake of potassium salts (by prescribing a diet rich in vegetables and fruits) and proteins. The appearance of side effects requires the withdrawal of the drug and the implementation of measures to regulate water-salt metabolism. Diuretics should be used in the case of the appearance of edemas.


Special instructions

  • Hypocorticism may occur with prolonged use of Prednisone(Prednisone Intensol, Rayos).
  • Prednisone is contraindicated in the case of the increased individual sensitivity to the drug or its components.
  • It is also contraindicated in the presence of peptic ulcer of the stomach and duodenum, thrombophlebitis and thromboembolic phenomena, mental disorders, hypertension, cardiac decompensation, acute endocarditis, osteoporosis, and pregnancy.
  • It is necessary to observe a rule of gradual reduction of the dose of the drug at the end of treatment (since there may be a corticosteroid withdrawal syndrome).
  • The use of prednisone during pregnancy is contraindicated.